Search results for " ivabradine"

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Old and New Drugs for Treatment of Advanced Heart Failure.

2020

Background: Advanced heart failure (HF) is a progressive disease with high mortality and limited medical therapeutic options. Long-term mechanical circulatory support and heart transplantation remain goldstandard treatments for these patients; however, access to these therapies is limited by the advanced age and multiple comorbidities of affected patients, as well as by the limited number of organs available. Methods: Traditional and new drugs available for the treatment of advanced HF have been researched. Results: To date, the cornerstone for the treatment of patients with advanced HF remains water restriction, intravenous loop diuretic therapy and inotropic support. However, many patien…

Inotropemedicine.medical_specialtymedicine.drug_classmedicine.medical_treatment030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineFurosemideDrug DiscoverymedicineHumansDecompensation030212 general & internal medicine: Dobutamine dopamine nitroglycerine sodium nitroprusside vaptans ivabradineIntensive care medicineDiureticsSimendanPharmacologyHeart transplantationHeart Failurebusiness.industryLevosimendanLoop diureticmedicine.diseasePrognosisOmecamtiv mecarbilIstaroximeHeart failurebusinessmedicine.drugCurrent pharmaceutical design
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Comparison of Ivabradine Versus Metoprolol in Early Phases of Reperfused Anterior Myocardial Infarction With Impaired Left Ventricular Function: Prel…

2009

BACKGROUND: beta-blockers in ST-segment elevation myocardial infarction (STEMI) are indicated for patients without a contraindication, particularly in patients with high heart rates (HR) or blood pressures. Epidemiological studies have shown that elevated HR represents a risk factor for cardiovascular morbidity. The study investigates the feasibility, tolerability, and the effects after 30 days of follow-up of ivabradine (IVA) versus metoprolol (METO) in early phases of anterior STEMI reperfused by percutaneous coronary intervention (PCI). METHODS AND RESULTS: Patients with a first anterior STEMI, Killip class I-II, an acceptable echocardiographic window, and admitted within 4hours of the o…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentMyocardial InfarctionMyocardial Reperfusion InjuryPilot ProjectsVentricular Dysfunction LeftDouble-Blind MethodInternal medicineejection fraction end systole volume ivabradinemedicineHumansIvabradinecardiovascular diseasesMyocardial infarctionAgedMetoprololKillip classEjection fractionbusiness.industryPercutaneous coronary interventionBenzazepinesMiddle Agedmedicine.diseasesurgical procedures operativeConventional PCICardiologyMyocardial infarction complicationsFemaleCardiology and Cardiovascular MedicinebusinessIvabradineFollow-Up StudiesMetoprololmedicine.drugJournal of Cardiac Failure
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